FGD4 (FYVE, RhoGEF and PH Domain Containing 4, FGD4)
Short Description: This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq, Oct 2008].
More information related to gene FGD4.
More information related to gene FGD4.
Products related to FGD4 Gene:
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62 results
OriGene rg219442
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- FYVE, RhoGEF and PH Domain Containing 4 (FGD4)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5446819
$781.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr314738
RNAi
FGD4
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- FYVE, RhoGEF and PH Domain Containing 4
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3311740
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to FGD4
- FYVE, RhoGEF and PH domain containing 4 (FGD4)
- FYVE, RhoGEF and PH domain containing 4 (Fgd4)
- 9030023J02Rik
- 9330209B17Rik
- CMT4H
- FRABP
- Frabp
- ZFYVE6
Gene-IDs for different species
Protein level used designations for FGD4
- FGD1 family, member 4
- FGD1-related F-actin-binding protein
- FYVE, RhoGEF and PH domain-containing protein 4
- actin-filament binding protein frabin
- zinc finger FYVE domain-containing protein 6
- Fgd1-related F-actin-binding protein
- actin filament-binding protein frabin
- frabin
Proteomics products related to FGD4 Gene
Other products related to FGD4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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