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FGFR4 (Fibroblast Growth Factor Receptor 4, FGFR4)

Short Description: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. [provided by RefSeq, Jul 2008].
More information related to gene FGFR4.

Products related to FGFR4 Gene:

74 results

ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Fibroblast Growth Factor Receptor 4 (FGFR4)
NCBI Accession:
NM_001291980
Gene ID:
2264 (Human, FGFR4)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943829
$559.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Fibroblast Growth Factor Receptor 4 (FGFR4)
NCBI Accession:
NM_022963
Gene ID:
2264 (Human, FGFR4)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943830
$769.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Fibroblast Growth Factor Receptor 4 (FGFR4)
NCBI Accession:
NM_002011
Gene ID:
2264 (Human, FGFR4)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4919674
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
OriGene sr301587 RNAi FGFR4 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Fibroblast Growth Factor Receptor 4
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3341374
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-XL5
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to FGFR4

  • fibroblast growth factor receptor 4 (FGFR4)
  • fibroblast growth factor receptor 4 (fgfr4)
  • fibroblast growth factor receptor 4 (Fgfr4)
  • fibroblast growth factor receptor 4 S homeolog (fgfr4.S)
  • cd334
  • CD334
  • etID309818.21
  • fgfr-4
  • Fgfr-4
  • fgfr-4c
  • FGFR4
  • fgfr4
  • jtk2
  • JTK2
  • tkf
  • TKF
  • wu:fc13h10
  • XFGFR-4
  • XFGFR-4a
  • xfgfr4
  • zgc:111935

Gene-IDs for different species

Protein level used designations for FGFR4

  • fibroblast growth factor receptor 4
  • FGF receptor 4
  • FGFR-4
  • hydroxyaryl-protein kinase
  • protein-tyrosine kinase
  • tyrosine kinase related to fibroblast growth factor receptor
  • tyrosylprotein kinase
  • CTLA-2-beta protein
  • fibroblast growth factor receptor 4 16 minus form
  • protein-tyrosine kinase receptor MPK-11
  • fibroblast growth factor receptor FREK
  • fibroblast growth factor receptor-like embryonic kinase
  • fibroblast growth factor receptor 4c
Other products related to FGFR4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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