FKBP4 (FK506 Binding Protein 4, 59kDa, FKBP4)
Short Description: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008].
More information related to gene FKBP4.
More information related to gene FKBP4.
Products related to FKBP4 Gene:
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52 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- FK506 Binding Protein 4, 59kDa (FKBP4)
- NCBI Accession:
- NM_002014
- Gene ID:
- 2288 (Human, FKBP4)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4939427
$319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sr301601
RNAi
FKBP4
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- FK506 Binding Protein 4, 59kDa
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3341388
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to FKBP4
- FK506 binding protein 4 (FKBP4)
- FK506 binding protein 4 S homeolog (fkbp4.S)
- FK506 binding protein 4 (fkbp4)
- FK506 binding protein 4 (Fkbp4)
- 59kDa
- AL022792
- AW208983
- FKBP-4
- FKBP-52
- FKBP51
- fkbp52
- FKBP52
- fkbp59
- FKBP59
- FKPB52
- HBI
- hsp56
- Hsp56
- MGC81078
- p52
- p59
- P59
- PPIase
- wu:fb34f09
Gene-IDs for different species
Protein level used designations for FKBP4
- peptidyl-prolyl cis-trans isomerase FKBP4
- FK506-binding protein 4
- FK506 binding protein 4, 59kDa
- peptidyl-prolyl cis-trans isomerase FKBP4-like
- 52 kDa FK506-binding protein
- 52 kDa FKBP
- 59 kDa immunophilin
- FKBP59
- HBI
- HSP-binding immunophilin
- PPIase FKBP4
- immunophilin FKBP52
- rotamase
- FK506 binding protein 52
- FKBP52 protein
- 51 kDa FK506-binding protein
- FK506-binding protein 4 (59kD)
- HSP binding immunophilin
- T-cell FK506-binding protein, 59kD
- peptidylprolyl cis-trans isomerase
- hsp90 binding protein
- p59 protein
Proteomics products related to FKBP4 Gene
Other products related to FKBP4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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