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FLT3 (Fms-Related tyrosine Kinase 3, FLT3)
Short Description: This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jul 2008].
More information related to gene FLT3.
Products related to FLT3 Gene:
Recommended next Filters:
OriGene rc211459l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6411070
$1,893.87
Plus shipping costs $50.00, if applicable $20.00 dry ice
Delivery in 21 to 27 Business Days
OriGene rc211459l2v
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
Type:
ORF
Application:
Protein Expression
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN6411071
$1,893.87
Plus shipping costs $50.00, if applicable $20.00 dry ice
Delivery in 21 to 27 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Type:
ORF
Application:
Cloning
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Gene ID:
2322 (Human, FLT3)
Vector type:
Gateway Cloning Vector
Resistance Gene:
Spectinomycin
Catalog No. ABIN5325628
$246.97
Plus shipping costs $50.00
Delivery in 15 to 19 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Type:
ORF
Application:
Cloning
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Gene ID:
2322 (Human, FLT3)
Vector type:
Gateway Cloning Vector
Resistance Gene:
Spectinomycin
Catalog No. ABIN5325977
$235.38
Plus shipping costs $50.00
Delivery in 15 to 19 Business Days
OriGene tl320361
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3764490
$1,002.87
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene tf515103
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Mouse
Vector type:
Retroviral Vector
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3677397
$874.17
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene tf320361
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Human
Vector type:
Retroviral Vector
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3723814
$874.17
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
OriGene tg515103
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Mouse
Vector type:
Retroviral Vector
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3697096
$707.85
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene tg320361
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Human
Vector type:
Retroviral Vector
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3744152
$707.85
Plus shipping costs $50.00
Delivery in 16 to 17 Business Days
OriGene tr320361
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fms-Related tyrosine Kinase 3 (FLT3)
Species:
Human
Vector type:
Retroviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3661249
$874.17
Plus shipping costs $50.00
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to FLT3
fms related tyrosine kinase 3 (FLT3)
FMS-like tyrosine kinase 3 (Flt3)
fms-related tyrosine kinase 3 (Flt3)
fms related tyrosine kinase 3 (Flt3)
B230315G04
CD135
Flk-2
FLK-2
Flk2
FLK2
Flt-3
FLT3
Ly72
STK1
wmfl
Gene-IDs for different species
Protein level used designations for FLT3
fms-related tyrosine kinase 3
FL cytokine receptor-like
FL cytokine receptor
fetal liver kinase 2
receptor-type tyrosine-protein kinase FLT3
tyrosine-protein kinase FLT3
tyrosine-protein kinase receptor flk-2
CD135 antigen
STK-1
fms-like tyrosine kinase 3
growth factor receptor tyrosine kinase type III
stem cell tyrosine kinase 1
FMS-like tyrosine kinase 3
Other products related to FLT3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website
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