FLT3 (Fms-Related tyrosine Kinase 3, FLT3)
Short Description: This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jul 2008].
More information related to gene FLT3.
More information related to gene FLT3.
Products related to FLT3 Gene:
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56 results
OriGene rg211459
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fms-Related tyrosine Kinase 3 (FLT3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5423491
$1,547.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc211459
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fms-Related tyrosine Kinase 3 (FLT3)
- NCBI Accession:
- NM_004119,NP_004110
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5423492
$1,349.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc211459l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fms-Related tyrosine Kinase 3 (FLT3)
- NCBI Accession:
- NM_004119,NP_004110
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5423494
$1,646.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rr217404
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fms-Related tyrosine Kinase 3 (FLT3)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5423493
$996.93
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc211459l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fms-Related tyrosine Kinase 3 (FLT3)
- NCBI Accession:
- NM_004119,NP_004110
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5423495
$1,646.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr301629
RNAi
FLT3
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Fms-Related tyrosine Kinase 3
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3341416
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to FLT3
- fms related tyrosine kinase 3 (FLT3)
- FMS-like tyrosine kinase 3 (Flt3)
- fms-related tyrosine kinase 3 (Flt3)
- fms related tyrosine kinase 3 (Flt3)
- B230315G04
- CD135
- Flk-2
- FLK-2
- Flk2
- FLK2
- Flt-3
- FLT3
- Ly72
- STK1
- wmfl
Gene-IDs for different species
Protein level used designations for FLT3
- fms-related tyrosine kinase 3
- FL cytokine receptor-like
- FL cytokine receptor
- fetal liver kinase 2
- receptor-type tyrosine-protein kinase FLT3
- tyrosine-protein kinase FLT3
- tyrosine-protein kinase receptor flk-2
- CD135 antigen
- STK-1
- fms-like tyrosine kinase 3
- growth factor receptor tyrosine kinase type III
- stem cell tyrosine kinase 1
- FMS-like tyrosine kinase 3
Proteomics products related to FLT3 Gene
Other products related to FLT3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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