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FZR1 (Fizzy/cell Division Cycle 20 Related 1, FZR1)

Short Description: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
More information related to gene FZR1.

Products related to FZR1 Gene:

63 results

OriGene tl503165 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3515789
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl706618 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3514768
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr706618 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3440024
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr415887 RNAi FZR1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Fizzy/cell Division Cycle 20 Related 1
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3271943
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc325888 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Fizzy/cell Division Cycle 20 Related 1 (FZR1)
NCBI Accession:
NM_001136197,NP_001129669
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3300975
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc325997 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Fizzy/cell Division Cycle 20 Related 1 (FZR1)
NCBI Accession:
NM_001136198,NP_001129670
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3300976
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr502398 RNAi FZR1 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Fizzy/cell Division Cycle 20 Related 1
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3352596
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn506212 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3235430
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn401413 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3235429
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn202684 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_001108074,NP_001101544
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3289375
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FZR1

  • fizzy and cell division cycle 20 related 1 (Fzr1)
  • fizzy/cell division cycle 20 related 1 (CDH1-C)
  • fizzy and cell division cycle 20 related 1 (FZR1)
  • fizzy-related protein homolog (LOC100027495)
  • fizzy-related protein homolog (LOC100179951)
  • fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1)
  • fizzy/cell division cycle 20 related 1a (fzr1a)
  • AW108046
  • CDC20C
  • CDH1
  • Cdh1
  • CDH1-C
  • FYR
  • Fyr
  • FZR
  • fzr1
  • FZR2
  • HCDH
  • HCDH1
  • zgc:55450

Gene-IDs for different species

Protein level used designations for FZR1

  • fizzy-related protein homolog
  • fizzy/cell division cycle 20 related 1 (Drosophila)
  • fizzy-related protein FZR
  • Fizzy-related protein-like protein
  • fizzy/cell division cycle 20 related 1
  • CDC20-like 1b
  • CDC20-like protein 1
  • cdh1/Hct1 homolog
  • cell division cycle 20 related 1
Other products related to FZR1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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