FZR1 (Fizzy/cell Division Cycle 20 Related 1, FZR1)
Short Description: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
More information related to gene FZR1.
More information related to gene FZR1.
Products related to FZR1 Gene:
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OriGene rc201413
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
- NCBI Accession:
- NM_016263,NP_057347
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5401968
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc226613
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
- NCBI Accession:
- NM_001136197,NP_001129669
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5401969
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc201413l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
- NCBI Accession:
- NM_016263,NP_057347
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5401972
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to FZR1
- fizzy and cell division cycle 20 related 1 (Fzr1)
- fizzy/cell division cycle 20 related 1 (CDH1-C)
- fizzy and cell division cycle 20 related 1 (FZR1)
- fizzy-related protein homolog (LOC100027495)
- fizzy-related protein homolog (LOC100179951)
- fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1)
- fizzy/cell division cycle 20 related 1a (fzr1a)
- AW108046
- CDC20C
- CDH1
- Cdh1
- CDH1-C
- FYR
- Fyr
- FZR
- fzr1
- FZR2
- HCDH
- HCDH1
- zgc:55450
Gene-IDs for different species
Protein level used designations for FZR1
- fizzy-related protein homolog
- fizzy/cell division cycle 20 related 1 (Drosophila)
- fizzy-related protein FZR
- Fizzy-related protein-like protein
- fizzy/cell division cycle 20 related 1
- CDC20-like 1b
- CDC20-like protein 1
- cdh1/Hct1 homolog
- cell division cycle 20 related 1
Proteomics products related to FZR1 Gene
Other products related to FZR1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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