GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase, GNE)
Short Description: The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
More information related to gene GNE.
More information related to gene GNE.
Products related to GNE Gene:
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75 results
OriGene rc231354
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE)
- NCBI Accession:
- NM_001190383,NP_001177312
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5438529
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg222626
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5438521
$781.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc222626l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE)
- NCBI Accession:
- NM_005476,NP_005467
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5438538
$951.39
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc222626l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase (GNE)
- NCBI Accession:
- NM_005476,NP_005467
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5438532
$951.39
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr306746
RNAi
GNE
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3346503
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to GNE
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE)
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (gne)
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (Gne)
- 2310066H07Rik
- DMRV
- GLCNE
- GNE
- IBM2
- MGC145505
- NM
- UAE1
- Uae1
- zgc:77657
Gene-IDs for different species
Protein level used designations for GNE
- UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase
- bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
- bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase-like
- N-acylmannosamine kinase
- UDP-GlcNAc-2-epimerase/ManAc kinase
- UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
- UDP-N-acetylglucosamine-2-epimerase/N- acetylmannosamine kinase
Proteomics products related to GNE Gene
Other products related to GNE such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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