Granulin (Granulin, GRN)
Short Description: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008].
More information related to gene Granulin.
More information related to gene Granulin.
Products related to Granulin Gene:
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73 results
OriGene rc202139
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Granulin (GRN)
- NCBI Accession:
- NM_002087,NP_002078
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5416523
$546.48
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr200396
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Granulin (GRN)
- NCBI Accession:
- NM_017113,NP_058809
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5416524
$609.84
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene sr301948
RNAi
GRN
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Granulin
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3341733
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to Granulin
- granulin precursor (GRN)
- granulin a (grna)
- Granulins (grn)
- granulin L homeolog (grn.L)
- granulin (granulin)
- granulin (ORF1 granulin)
- granulin precursor (Grn)
- granulin (Grn)
- acrogranin
- CLN11
- DKFZp459H066
- epithelin
- GEP
- GP88
- GRN
- grn
- MGC53354
- PCDGF
- PEPI
- PGRN
- wu:fb11g12
- wu:fj18f05
Gene-IDs for different species
Protein level used designations for Granulin
- granulin
- granulin-a
- zfPGRN-A
- Granulins
- PC cell-derived growth factor
- acrogranin
- granulin-epithelin
- granulins
- proepithelin
- progranulin
- PCDGF
- PEPI
- acrogranulin
Proteomics products related to Granulin Gene
Other products related to Granulin such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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