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GREM1 (Gremlin 1, GREM1)

Short Description: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
More information related to gene GREM1.

Products related to GREM1 Gene:

71 results

OriGene sr308880 RNAi GREM1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Gremlin 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3284918
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pCMV6-XL4
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to GREM1

  • gremlin 1a, DAN family BMP antagonist (grem1a)
  • gremlin 1, DAN family BMP antagonist (GREM1)
  • gremlin 1 (LOC662541)
  • gremlin 1, DAN family BMP antagonist (grem1)
  • gremlin 1, DAN family BMP antagonist (Grem1)
  • gremlin 1, DAN family BMP antagonist L homeolog (grem1.L)
  • Cktsf1b1
  • CKTSF1B1
  • cktsf1b1
  • dand2
  • DAND2
  • drm
  • Drm
  • DRM
  • Grem
  • grem1
  • GREM1
  • gremlin
  • GREMLIN
  • gremlin-1
  • ihg-2
  • IHG-2
  • ld
  • MGC136702
  • pig2
  • zgc:136702

Gene-IDs for different species

Protein level used designations for GREM1

  • gremlin 1 homolog a, cysteine knot superfamily
  • gremlin 1 homolog, cysteine knot superfamily
  • gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)
  • gremlin 1
  • GLEAN_07044
  • cysteine knot superfamily 1
  • cysteine knot superfamily 1, BMP antagonist 1
  • down-regulated in Mos-transformed cells protein
  • down-regulated in v-mos-transformed cells
  • gremlin-1
  • gremlin 1, cysteine knot superfamily, homolog
  • Cysteine knot superfamily 1, BMP antagonist 1
  • DAN domain family member 2
  • cell proliferation-inducing gene 2 protein
  • gremlin 1-like protein
  • increased in high glucose-2
Other products related to GREM1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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