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HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase, HMGCL)

Short Description: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
More information related to gene HMGCL.

Products related to HMGCL Gene:

54 results

OriGene sc322255 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_000191,NP_000182
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3318975
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene sc120045 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_000191,NP_000182
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3384457
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene rc203817 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_000191,NP_000182
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5420938
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene rc228188 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_001166059,NP_001159531
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5420939
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene sc326823 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_001166059,NP_001159531
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3301446
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rn214875 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_024386,NP_077362
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3325260
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rr214875 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
NCBI Accession:
NM_024386,NP_077362
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5420940
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rg203817 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5420936
$495.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rg228188 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5420937
$495.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene sr410818 RNAi HMGCL Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3266917
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to HMGCL

  • 3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog (hmgcl.S)
  • 3-hydroxymethyl-3-methylglutaryl-CoA lyase (HMGCL)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (AFUA_7G01720)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (NFIA_114450)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (ACLA_065820)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (AOR_1_910074)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (PMAA_004600)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (TSTA_103060)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (ARB_04874)
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (TRV_06573)
  • 3-hydroxy-3-methylglutaryl-Coenzyme A lyase (Hmgcl)
  • 3-hydroxymethyl-3-methylglutaryl-CoA lyase (Hmgcl)
  • 3-hydroxymethyl-3-methylglutaryl-CoA lyase (hmgcl)
  • Afu7g01720
  • AO090038000541
  • AW476067
  • HL
  • zgc:56248

Gene-IDs for different species

Protein level used designations for HMGCL

  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase
  • 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
  • 3-hydroxy-3-methylglutarate-CoA lyase
  • HL
  • HMG-CoA lyase
  • hydroxymethylglutaryl-CoA lyase, mitochondrial
  • 3-hydroxy-3-methylglutaryl-CoA lyase
  • hydroxymethylglutaricaciduria
  • mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
  • 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
Other products related to HMGCL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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