HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2, HSD11B2)
Short Description: There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010].
More information related to gene HSD11B2.
More information related to gene HSD11B2.
Products related to HSD11B2 Gene:
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56 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- NCBI Accession:
- NM_000196
- Gene ID:
- 3291 (Human, HSD11B2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4928672
$319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene sc122552
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- NCBI Accession:
- NM_000196,NP_000187
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3390154
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rc207796
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- NCBI Accession:
- NM_000196,NP_000187
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5390928
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg207796
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5390927
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr412992
RNAi
HSD11B2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3269072
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sr506331
RNAi
HSD11B2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3355964
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr302241
RNAi
HSD11B2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342023
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rr206617
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- NCBI Accession:
- NM_017081,NP_058777
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5390929
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
OriGene tg501002
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3683047
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf709892
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3490170
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to HSD11B2
- hydroxysteroid (11-beta) dehydrogenase 2 L homeolog (hsd11b2.L)
- hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2)
- hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2)
- 11-HSD2
- 11HSD2
- AME
- AME1
- HSD2
- HSD11B2
- HSD11K
- MGC81883
- SDR9C3
Gene-IDs for different species
Protein level used designations for HSD11B2
- hydroxysteroid (11-beta) dehydrogenase 2
- corticosteroid 11-beta-dehydrogenase isozyme 2
- 11 beta-hydroxysteroid dehydrogenase type 2
- -HSD11 type II
- 11-DH2
- 11-beta-HSD2
- 11-beta-hydroxysteroid dehydrogenase type 2
- 11-beta-hydroxysteroid dehydrogenase type II
- NAD-dependent 11-beta-hydroxysteroid dehydrogenase
- short chain dehydrogenase/reductase family 9C member 3
- 11-beta hydroxysteroid dehydrogenase
- hydroxysteroid 11-beta dehydrogenase 2
- 11-beta-hydroxysteroid dehydrogenase 2
- 11(beta)-HSD2
- Hydroxysteroid dehydrogenase, 11 beta type 2
Proteomics products related to HSD11B2 Gene
Other products related to HSD11B2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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