HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2, HSD11B2)
Short Description: There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010].
More information related to gene HSD11B2.
More information related to gene HSD11B2.
Products related to HSD11B2 Gene:
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56 results
OriGene rc207796l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6405256
$996.93
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
OriGene tl312327
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3757508
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl501002
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3702747
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl709892
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3447174
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn507964
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3238450
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn407796
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3238449
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to HSD11B2
- hydroxysteroid (11-beta) dehydrogenase 2 L homeolog (hsd11b2.L)
- hydroxysteroid 11-beta dehydrogenase 2 (HSD11B2)
- hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2)
- 11-HSD2
- 11HSD2
- AME
- AME1
- HSD2
- HSD11B2
- HSD11K
- MGC81883
- SDR9C3
Gene-IDs for different species
Protein level used designations for HSD11B2
- hydroxysteroid (11-beta) dehydrogenase 2
- corticosteroid 11-beta-dehydrogenase isozyme 2
- 11 beta-hydroxysteroid dehydrogenase type 2
- -HSD11 type II
- 11-DH2
- 11-beta-HSD2
- 11-beta-hydroxysteroid dehydrogenase type 2
- 11-beta-hydroxysteroid dehydrogenase type II
- NAD-dependent 11-beta-hydroxysteroid dehydrogenase
- short chain dehydrogenase/reductase family 9C member 3
- 11-beta hydroxysteroid dehydrogenase
- hydroxysteroid 11-beta dehydrogenase 2
- 11-beta-hydroxysteroid dehydrogenase 2
- 11(beta)-HSD2
- Hydroxysteroid dehydrogenase, 11 beta type 2
Proteomics products related to HSD11B2 Gene
Other products related to HSD11B2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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