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HYOU1 (Hypoxia Up Regulated 1, HYOU1)

Short Description: The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. [provided by RefSeq, Oct 2008].
More information related to gene HYOU1.

Products related to HYOU1 Gene:

63 results

OriGene rr200176 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Hypoxia Up Regulated 1 (HYOU1)
NCBI Accession:
NM_138867,NP_620222
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5376483
$994.95
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Hypoxia Up Regulated 1 (HYOU1)
NCBI Accession:
NM_001130991
Gene ID:
10525 (Human, HYOU1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4919380
$679.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
OriGene sr307153 RNAi HYOU1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Hypoxia Up Regulated 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3346907
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Rat
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to HYOU1

  • hypoxia up-regulated 1 (HYOU1)
  • hypoxia up-regulated 1 (Hyou1)
  • hypoxia up-regulated 1 (hyou1)
  • hypoxia up-regulated protein 1 (LOC100380749)
  • hypoxia up-regulated 1 S homeolog (hyou1.S)
  • AI415631
  • Cab140
  • CBP-140
  • GRP-170
  • Grp170
  • GRP170
  • HSP12A
  • HYOU1
  • id:ibd5056
  • ORP-150
  • ORP150
  • Orp150
  • orp150
  • wu:fd14c05
  • zgc:56019

Gene-IDs for different species

Protein level used designations for HYOU1

  • 150 kDa oxygen-regulated protein
  • 170 kDa glucose-regulated protein
  • glucose-regulated protein 170
  • hypoxia up-regulated protein 1
  • oxygen regulated protein (150kD)
  • 140 kDa Ca(2+)-binding protein
  • 150-kDa oxygen regulated protein
  • 170 kDa glucose regulated protein GRP170
  • GRP-170
  • calcium binding protein 140
  • calcium binding protein, 140 kDa
  • ORP-150
  • hypoxia up-regulated 1
  • Hypoxia up-regulated protein 1
  • hypoxia up-regulated protein 1-like
  • glucose regulated protein, 170 kDa
  • oxygen regulated protein, 150 kDa
Other products related to HYOU1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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