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IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble, IDH1)

Short Description: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008].
More information related to gene IDH1.

Products related to IDH1 Gene:

74 results

OriGene rr204198 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
NCBI Accession:
NM_031510,NP_113698
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5436032
$286.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rc210582l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
NCBI Accession:
NM_005896,NP_005887
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5436033
$976.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene rc210582l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
NCBI Accession:
NM_005896,NP_005887
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5436035
$976.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene sr302305 RNAi IDH1 Species: Human HPLC purified
Pubmed 1
Application:
RNA Interference
Gene:
Isocitrate Dehydrogenase 1 (NADP+), Soluble
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3342087
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to IDH1

  • isocitrate dehydrogenase (NADP(+)) 1, cytosolic (IDH1)
  • isocitrate dehydrogenase 1 (NADP+), soluble (Idh1)
  • isocitrate dehydrogenase (NADP(+)) 1, cytosolic (Idh1)
  • isocitrate dehydrogenase 1 (NADP+) L homeolog (idh1.L)
  • isocitrate dehydrogenase 1 (NADP+), soluble (idh1)
  • isocitrate dehydrogenase 1 (IDH1)
  • AI314845
  • AI788952
  • cb876
  • E030024J03Rik
  • F23E12.180
  • F23E12_180
  • fm90e09
  • Id-1
  • IDCD
  • IDH
  • Idh-1
  • IDH-I
  • IDP
  • IDPC
  • Idpc
  • im:7143416
  • isocitrate dehydrogenase 1
  • isocitrate dehydrogenase I
  • NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1
  • NADP-CICDH
  • PICD
  • wu:fm90e09

Gene-IDs for different species

Protein level used designations for IDH1

  • NADP(+)-specific ICDH
  • NADP-dependent isocitrate dehydrogenase, cytosolic
  • NADP-dependent isocitrate dehydrogenase, peroxisomal
  • isocitrate dehydrogenase [NADP] cytoplasmic
  • oxalosuccinate decarboxylase
  • IDH
  • IDP
  • cytosolic NADP-isocitrate dehydrogenase
  • isocitrate dehydrogenase 1 (NADP+), soluble
  • isocitrate dehydrogenase [NADP] cytoplasmic-like
  • Isocitrate dehydrogenase 1, soluble
  • isocitrate dehydrogenase 1
  • IDH-I
  • Isocitric dehydrogenase 1
  • NAD(+)-specific ICDH 1
Other products related to IDH1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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