INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa, INPP5D)
Short Description: This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
More information related to gene INPP5D.
More information related to gene INPP5D.
Products related to INPP5D Gene:
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83 results
OriGene tl710316
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3447597
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg710316
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3504524
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl516227
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3528816
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr710316
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3435206
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr422352
RNAi
INPP5D
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3349206
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr510337
RNAi
INPP5D
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3359399
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene kn508348
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3239225
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn412176
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3239224
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc223682
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_001110193,NP_001103663
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3326344
$1,559.25
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene mc223875
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_001110192,NP_001103662
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3326345
$1,128.60
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
Synonyms and alternative names related to INPP5D
- inositol polyphosphate-5-phosphatase D (INPP5D)
- phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045)
- inositol polyphosphate-5-phosphatase D (inpp5d)
- inositol polyphosphate 5-phosphatase (EHI_159880)
- inositol polyphosphate 5-phosphatase (EHI_153490)
- inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L)
- phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693)
- inositol polyphosphate-5-phosphatase D (Inpp5d)
- 13.t00027
- 256.t00004
- AI323613
- hp51CN
- INPP5D
- s-SHIP
- ship
- SHIP
- SHIP-1
- ship1
- SHIP1
- SIP-145
Gene-IDs for different species
Protein level used designations for INPP5D
- inositol polyphosphate-5-phosphatase, 145kDa
- SH2 containing inositol phosphatase
- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like
- SH2 domain-containing inositol 5'-phosphatase 1
- SH2 domain-containing inositol phosphatase 1
- SH2 domain-containing inositol-5'-phosphatase 1
- SHIP-1
- phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
- Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
- SH2 containing inositol phosphotase
- SH2-containing inositol phosphatase SHIP
- SIP-145
- Src homology 2 domain-containing inositol-5-phosphatase
- inositol polyphosphate-5-phosphatase of 145 kDa
- inositol polyphosphate-5-phosphatase, 145 kDa
- p150Ship
- Inositol polyphosphate-5-phosphatase 145 kDa
- Inositol polyphosphate-5-phosphatase, 145 kDa
- signaling inositol polyphosphate 5 phosphatase SIP-145
Proteomics products related to INPP5D Gene
Other products related to INPP5D such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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