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INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa, INPP5D)

Short Description: This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
More information related to gene INPP5D.

Products related to INPP5D Gene:

83 results

OriGene sc116675 cDNA PExp Mammalian Expression Vector pCMV6-XL6 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
NCBI Accession:
NM_005541,NP_005532
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, SP6 Promoter
Expression:
Transient
Catalog No. ABIN3393569
$1,024.65
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rr210625 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5335186
$1,127.61
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene sr302430 RNAi INPP5D Species: Human HPLC purified
Application:
RNA Interference
Gene:
Inositol Polyphosphate-5-Phosphatase, 145kDa
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3342212
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL6
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to INPP5D

  • inositol polyphosphate-5-phosphatase D (INPP5D)
  • phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045)
  • inositol polyphosphate-5-phosphatase D (inpp5d)
  • inositol polyphosphate 5-phosphatase (EHI_159880)
  • inositol polyphosphate 5-phosphatase (EHI_153490)
  • inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L)
  • phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693)
  • inositol polyphosphate-5-phosphatase D (Inpp5d)
  • 13.t00027
  • 256.t00004
  • AI323613
  • hp51CN
  • INPP5D
  • s-SHIP
  • ship
  • SHIP
  • SHIP-1
  • ship1
  • SHIP1
  • SIP-145

Gene-IDs for different species

Protein level used designations for INPP5D

  • inositol polyphosphate-5-phosphatase, 145kDa
  • SH2 containing inositol phosphatase
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
  • phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like
  • SH2 domain-containing inositol 5'-phosphatase 1
  • SH2 domain-containing inositol phosphatase 1
  • SH2 domain-containing inositol-5'-phosphatase 1
  • SHIP-1
  • phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
  • Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
  • SH2 containing inositol phosphotase
  • SH2-containing inositol phosphatase SHIP
  • SIP-145
  • Src homology 2 domain-containing inositol-5-phosphatase
  • inositol polyphosphate-5-phosphatase of 145 kDa
  • inositol polyphosphate-5-phosphatase, 145 kDa
  • p150Ship
  • Inositol polyphosphate-5-phosphatase 145 kDa
  • Inositol polyphosphate-5-phosphatase, 145 kDa
  • signaling inositol polyphosphate 5 phosphatase SIP-145
Other products related to INPP5D such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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