KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1, KLKB1)
Short Description: Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. [provided by RefSeq, Jul 2008].
More information related to gene KLKB1.
More information related to gene KLKB1.
Products related to KLKB1 Gene:
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59 results
OriGene kn508912
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3240437
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn411985
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3240436
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn203779
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- NCBI Accession:
- NM_012725,NP_036857
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3327543
$883.08
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene sc119592
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- NCBI Accession:
- NM_000892,NP_000883
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3378621
$589.05
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rr203779
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- NCBI Accession:
- NM_012725,NP_036857
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5480828
$882.09
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg211985
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5381554
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc211985
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- NCBI Accession:
- NM_000892,NP_000883
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5381555
$588.06
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1)
- NCBI Accession:
- NM_000892
- Gene ID:
- 3818 (Human, KLKB1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4938172
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sr302581
RNAi
KLKB1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Kallikrein B, Plasma (Fletcher Factor) 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342363
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to KLKB1
- kallikrein B1 (KLKB1)
- kallikrein B, plasma 1 (Klkb1)
- kallikrein B1 (Klkb1)
- plasma kallikrein (CpipJ_CPIJ004042)
- plasma kallikrein (CpipJ_CPIJ014955)
- plasma kallikrein (CpipJ_CPIJ020108)
- Plasma kallikrein (VAA_02266)
- kallikrein B, plasma (Fletcher factor) 1 (KLKB1)
- coagulation factor XI (LOC100549617)
- kallikrein B1 (klkb1)
- kallikrein B1 L homeolog (klkb1.L)
- APS
- DKFZp459J2015
- Kal-3
- Kal3
- Kalp1
- KALP15
- KLK3
- Klk3
- KLKB1
- klkb1
- PPK
- PSA
Gene-IDs for different species
Protein level used designations for KLKB1
- Fletcher factor
- kininogenin
- plasma kallikrein
- plasma kallikrein heavy chain
- plasma kallikrein light chain
- plasma prekallikrein
- antigen, prostate specific
- fletcher factor
- kallikrein 3, plasma
- kallikrein B, plasma (Fletcher factor) 1
- Plasma kallikrein
- plasma kallikrein-like
- plasma kallikrein B1
Proteomics products related to KLKB1 Gene
Other products related to KLKB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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