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KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1, KLRK1)

Short Description: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster. [provided by RefSeq, Dec 2010].
More information related to gene KLRK1.

Products related to KLRK1 Gene:

67 results

OriGene tg712660 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3506859
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl516197 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3528786
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr712660 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3437541
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr406412 RNAi KLRK1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3280390
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc322611 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
NCBI Accession:
NM_007360,NP_031386
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3319026
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sr509080 RNAi KLRK1 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3358331
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn508948 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3240486
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn208050 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3240485
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 10 to 13 Business Days
OriGene mc226400 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
NCBI Accession:
NM_001286018,NP_001272947
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3327608
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene rn209367 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1)
NCBI Accession:
NM_133512,NP_598196
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3327609
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC
    • pCMV6-AC-GFP
    • pCMV6-XL4
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to KLRK1

  • killer cell lectin like receptor K1 (KLRK1)
  • killer cell lectin-like receptor subfamily K, member 1 (KLRK1)
  • killer cell lectin-like receptor subfamily K, member 1 (Klrk1)
  • killer cell lectin like receptor K1 (Klrk1)
  • NKG2D protein (NKG2D)
  • CD314
  • D6H12S2489E
  • D12S2489E
  • KLR
  • KLRK1
  • NKG2-D
  • NKG2D
  • Nkg2d
  • Nkrp2

Gene-IDs for different species

Protein level used designations for KLRK1

  • killer cell lectin-like receptor subfamily K, member 1
  • NKG2-D type II integral membrane protein-like
  • NK cell receptor D
  • NKG2-D type II integral membrane protein
  • NKG2-D-activating NK receptor
  • natural killer cell group 2D
  • NK lectin-like receptor
  • NKLLR
  • NKR-P2, ortholog of human NKG2D
  • killer cell lectin-like receptor subfamily K member 1
  • NKG2-D activating NK receptor
Other products related to KLRK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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