Laminin beta 1 (Laminin, beta 1, LAMB1)
Short Description: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis. [provided by RefSeq, Aug 2011].
More information related to gene Laminin beta 1.
More information related to gene Laminin beta 1.
Products related to Laminin beta 1 Gene:
Recommended next Filters:
42 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Laminin, beta 1 (LAMB1)
- NCBI Accession:
- NM_002291
- Gene ID:
- 3912 (Human, LAMB1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4946356
$1,359.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
OriGene sr302646
RNAi
LAMB1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Laminin, beta 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342428
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to Laminin beta 1
- laminin subunit beta 1 (LAMB1)
- laminin, beta 1a (lamb1a)
- laminin subunit beta 1 (Lamb1)
- laminin subunit beta 1 (lamb1)
- laminin B1 (Lamb1)
- C77966
- C80098
- C81607
- CLM
- D130003D08Rik
- fc20b05
- gup
- Lamb-1
- lamb1
- LAMB1
- Lamb1-1
- LIS5
- sb:cb95
- wu:fc20b05
Gene-IDs for different species
Protein level used designations for Laminin beta 1
- laminin B1 chain
- laminin subunit beta-1
- cb95
- grumpy
- laminin, beta 1
- laminin B1 subunit 1
- laminin B1
- laminin beta-1-1 chain
- laminin-1 subunit beta
- laminin-10 subunit beta
- laminin-12 subunit beta
- laminin-2 subunit beta
- laminin-6 subunit beta
- laminin-8 subunit beta
- laminin beta-1 chain
- laminin subunit beta-1-like
Proteomics products related to Laminin beta 1 Gene
Other products related to Laminin beta 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
