LIM Domain Kinase 1 (LIM Domain Kinase 1, LIMK1)
Short Description: There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Feb 2011].
More information related to gene LIM Domain Kinase 1.
More information related to gene LIM Domain Kinase 1.
Products related to LIM Domain Kinase 1 Gene:
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OriGene sr302692
RNAi
LIMK1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- LIM Domain Kinase 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342474
$512.82
Plus shipping costs $50.00
1 kit
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Synonyms and alternative names related to LIM Domain Kinase 1
- LIM domain kinase 1 (LIMK1)
- LIM domain kinase 1a (limk1a)
- LIM domain kinase 1 (limk1)
- LIM domain kinase 1 (CpipJ_CPIJ000717)
- LIM domain kinase 1 (LOC413152)
- LIM domain kinase 1 (Limk1)
- LIM domain kinase 1 L homeolog (limk1.L)
- LIM-domain containing, protein kinase (Limk1)
- GB16654
- LIMK
- LIMK-1
- limk1
- LIMK1
- xlimk1
Gene-IDs for different species
Protein level used designations for LIM Domain Kinase 1
- LIM domain kinase 1
- LIM-kinase1
- LIM motif-containing protein kinase
- LIM motif-containing protein kinase 1
- LIM-domain containing protein kinase 1
- LIM-domain containing, protein kinase 1
- LIMK-1
- chLIMK1
- KIZ-1
Proteomics products related to LIM Domain Kinase 1 Gene
Other products related to LIM Domain Kinase 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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