LIMK2 (LIM Domain Kinase 2, LIMK2)
Short Description: There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene LIMK2.
More information related to gene LIMK2.
Products related to LIMK2 Gene:
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72 results
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5317988
$226.33
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
OriGene sr302693
RNAi
LIMK2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- LIM Domain Kinase 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342475
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to LIMK2
- LIM domain kinase 2 L homeolog (limk2.L)
- LIM domain kinase 2 (limk2)
- LIM domain kinase 2 (LIMK2)
- LIM domain kinase 2 (Limk2)
- LIM motif-containing protein kinase 2 (Limk2)
- 9430059K01
- A930024P04Rik
- C85310
- LIMK
- LIMK2
- Limk2a
- Limk2b
- Link2
- wu:fa97c09
- wu:fk73e11
- xlimk2
- zgc:91990
Gene-IDs for different species
Protein level used designations for LIMK2
- XLIM-Kinases2
- LIM domain kinase 2
- LIM domain kinase 2-like
- LIM motif-containing protein kinase 2
- LIMK-2
- LIM kinase 2
- LIM-containing protein kinase 2a
- LIM-containing protein kinase 2t
- Limk2t-1 and Limk2t-2
Proteomics products related to LIMK2 Gene
Other products related to LIMK2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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