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MAN2B1 (Mannosidase, Alpha, Class 2B, Member 1, MAN2B1)

Short Description: This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
More information related to gene MAN2B1.

Products related to MAN2B1 Gene:

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59 results

Human MAN2B1 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
NCBI Accession:
NM_000528
Gene ID:
4125 (Human, MAN2B1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4937898
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 6 Business Days
Details
Details
Mouse MAN2B1 siRNA Oligo
OriGene sr421705 RNAi MAN2B1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Mannosidase, Alpha, Class 2B, Member 1
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3348565
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
Details
Details
Human MAN2B1 siRNA Oligo
OriGene sr302798 RNAi MAN2B1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Mannosidase, Alpha, Class 2B, Member 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3342580
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
Details
Details
Human MAN2B1 shRNA in Retroviral Vector (GFP tag)
OriGene tg311592 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3736440
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
Details
Details
Mouse MAN2B1 shRNA in Retroviral Vector (GFP tag)
OriGene tg501297 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3683340
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
Details
Details
Rat MAN2B1 shRNA in Retroviral Vector (RFP tag)
OriGene tf713792 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3494058
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
Details
Details
Rat MAN2B1 shRNA in Retroviral Vector (GFP tag)
OriGene tg713792 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3507989
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
Details
Details
Human MAN2B1 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
NCBI Accession:
NM_001173498
Gene ID:
4125 (Human, MAN2B1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4945716
$799.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 4 Business Days
Details
Details
Human MAN2B1 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc200638 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
NCBI Accession:
NM_000528,NP_000519
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5426277
$871.20
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
Details
Details
Human MAN2B1 cDNA Clone in Mammalian Expression Vector
OriGene sc319430 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1)
NCBI Accession:
NM_000528,NP_000519
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3317826
$872.19
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MAN2B1

  • mannosidase alpha class 2B member 1 (MAN2B1)
  • mannosidase, alpha, class 2B, member 1 (man2b1)
  • mannosidase 2, alpha B1 (Man2b1)
  • mannosidase alpha class 2B member 1 (Man2b1)
  • mannosidase, alpha, class 2B, member 1 (Man2b1)
  • AW107687
  • LAMAN
  • Laman
  • Manb
  • MANB

Gene-IDs for different species

Protein level used designations for MAN2B1

  • mannosidase, alpha, class 2B, member 1
  • lysosomal alpha-mannosidase (109.3 kD) (XF355)
  • lysosomal alpha-mannosidase
  • lysosomal alpha-mannosidase-like
  • lysosomal acid alpha-mannosidase
  • mannosidase alpha class 2B member 1
  • mannosidase alpha-B
  • mannosidase 2, alpha B1
  • mannosidase, alpha B, lysosomal
  • laman
Other products related to MAN2B1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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