MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8, MAP3K8)
Short Description: This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011].
More information related to gene MAP3K8.
More information related to gene MAP3K8.
Products related to MAP3K8 Gene:
Recommended next Filters:
63 results
OriGene rc211171l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6410643
$1,223.64
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
OriGene kn509741
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3242177
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn411171
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3242176
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to MAP3K8
- mitogen-activated protein kinase kinase kinase 8 (MAP3K8)
- mitogen-activated protein kinase kinase kinase 8 (map3k8)
- mitogen-activated protein kinase kinase kinase 8 (Map3k8)
- c-COT
- COT
- Cot
- Cot/Tpl2
- D17TPL2
- EST
- Est
- ESTF
- Estf
- MAP3K8
- MEKK8
- Tpl-2
- TPL2
- Tpl2
Gene-IDs for different species
Protein level used designations for MAP3K8
- mitogen-activated protein kinase kinase kinase 8
- Ewing sarcoma transformant
- cot (cancer Osaka thyroid) oncogene
- proto-oncogene c-Cot
- proto-oncogene serine/threoine protein kinase
- tumor progression locus 2
- COT proto-oncogene serine/threonine-protein kinase
- cancer Osaka thyroid oncogene
- cancer Osaka thyroid, oncogene
- mitogen activated protein kinase kinase kinase 8
- serine/threonine-protein kinase cot
- serine/threonine kinase (Tpl-2)
Proteomics products related to MAP3K8 Gene
Other products related to MAP3K8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
