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MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8, MAP3K8)

Short Description: This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011].
More information related to gene MAP3K8.

Products related to MAP3K8 Gene:

127 results:

Human MAP3K8 ORF Clone in Cloning Vector Plasmid

ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755180
$84.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

Mouse MAP3K8 cDNA Clone in TA-Cloning Vector Plasmid

cDNA Clon TA-Cloning Vector pMD18-T Simple Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_007746
Species:
Mouse
Vector type:
TA-Cloning Vector
Vector backbone:
pMD18-T Simple
Resistance Gene:
Ampicillin
Catalog No. ABIN3887303
$158.97
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 8 to 10 Business Days

Human MAP3K8 cDNA Clone in TA-Cloning Vector Plasmid

cDNA Clon TA-Cloning Vector pMD18-T Simple Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
TA-Cloning Vector
Vector backbone:
pMD18-T Simple
Resistance Gene:
Ampicillin
Catalog No. ABIN3887302
$158.97
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 8 to 10 Business Days

Human MAP3K8 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pCR4-TOPO Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
1326 (Human, MAP3K8)
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Catalog No. ABIN3998728
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Human MAP3K8 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pCR4-TOPO Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
1326 (Human, MAP3K8)
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Catalog No. ABIN3998729
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Cow MAP3K8 cDNA Clone in Mammalian Expression Vector Plasmid

cDNA PExp, Clon Mammalian Expression Vector pCMV-SPORT6 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
535622 (Cow, MAP3K8)
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3862981
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Mouse MAP3K8 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pCR4-TOPO Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
26410 (Mouse, MAP3K8)
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Catalog No. ABIN4004663
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Mouse MAP3K8 cDNA Clone in Cloning Vector Plasmid

cDNA Clon Cloning Vector pCR4-TOPO Ampicillin unconjugated
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
26410 (Mouse, MAP3K8)
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Catalog No. ABIN4004662
$162.44
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Mouse MAP3K8 qPCR Primer Pair Primer

qPCR MAP3K8 Species: Mouse
Application:
Quantitative real-time PCR
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8
Species:
Mouse
Catalog No. ABIN3194003
$164.38
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 12 to 16 Business Days

Human MAP3K8 qPCR Primer Pair Primer

qPCR MAP3K8 Species: Human
Application:
Quantitative real-time PCR
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8
Species:
Human
Catalog No. ABIN3189049
$164.38
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 12 to 16 Business Days

Human MAP3K8 ORF Clone in Gateway Cloning Vector Plasmid

ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
1326 (Human, MAP3K8)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5324799
$206.58
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 15 to 17 Business Days

Human MAP3K8 ORF Clone in Gateway Cloning Vector Plasmid

ORF PExp Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
1326 (Human, MAP3K8)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN3414730
$308.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Human MAP3K8 ORF Clone in Gateway Cloning Vector Plasmid

ORF PExp Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
Gene ID:
1326 (Human, MAP3K8)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN3427969
$308.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag) Plasmid

ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Gene ID:
1326 (Human, MAP3K8)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4919061
$319.00
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (HA tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV3-C-HA Kanamycin Enhanced CMV Promoter HA tag Transient,Stable
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV3-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Hygromycin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
HA tag
Expression:
Transient,Stable
Catalog No. ABIN3919457
$321.32
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 17 to 23 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (His tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV3-C-His Kanamycin Enhanced CMV Promoter His tag Transient,Stable
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV3-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Hygromycin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
His tag
Expression:
Transient,Stable
Catalog No. ABIN3919458
$321.32
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 17 to 23 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (MYC tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV3-C-Myc Kanamycin Enhanced CMV Promoter MYC tag Transient,Stable
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV3-C-Myc
Resistance Gene:
Kanamycin
Selection Marker:
Hygromycin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
MYC tag
Expression:
Transient,Stable
Catalog No. ABIN3919459
$321.32
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 17 to 23 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV3-N-FLAG Kanamycin Enhanced CMV Promoter DYKDDDDK Tag Transient,Stable
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV3-N-FLAG
Resistance Gene:
Kanamycin
Selection Marker:
Hygromycin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient,Stable
Catalog No. ABIN3919461
$321.32
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 17 to 23 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (HA tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV3-N-HA Kanamycin Enhanced CMV Promoter HA tag Transient,Stable
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV3-N-HA
Resistance Gene:
Kanamycin
Selection Marker:
Hygromycin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
HA tag
Expression:
Transient,Stable
Catalog No. ABIN3919463
$321.32
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 17 to 23 Business Days

Human MAP3K8 ORF Clone in Mammalian Expression Vector (His tag) Plasmid

ORF PExp Mammalian Expression Vector pCMV3-N-His Kanamycin Enhanced CMV Promoter His tag Transient,Stable
Type:
ORF
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8)
NCBI Accession:
NM_005204
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV3-N-His
Resistance Gene:
Kanamycin
Selection Marker:
Hygromycin
Promoter:
Enhanced CMV Promoter
Fusion Tag:
His tag
Expression:
Transient,Stable
Catalog No. ABIN3919464
$321.32
Plus shipping costs $45.00
local_shipping Shipping to: United States
Delivery in 17 to 23 Business Days
  • Type
    • Plasmid
    • Primer
  • Species
    • Human
    • Mouse
    • Rat
    • Cow
  • Publication
  • Image
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Quantitative real-time PCR (qPCR)
  • Fusion tag
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • ZsGreen
    • HA tag
    • DYKDDDDK Tag
    • GFPSpark
    • MYC tag
    • OFPSpark
    • DYKDDDDK Tag,HA tag
    • DYKDDDDK Tag,His tag
    • His-GST
    • His-MBP
    • RFP tag
    • V5 tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pZIP-mCMV-ZsGreen
    • pCMV6-Entry
    • pCR4-TOPO
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-C-His
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pPM-N-D-C-HA
    • pPM-N-D-C-His
    • pRFP-C-RS
    • pRS
    • pCLIP-dual-SFFV-ZsGreen
    • pCMV3-C-FLAG
    • pCMV3-C-GFPSpark
    • pCMV3-C-HA
    • pCMV3-C-His
    • pCMV3-C-Myc
    • pCMV3-C-OFPSpark
    • pCMV3-N-FLAG
    • pCMV3-N-GFPSpark
    • pCMV3-N-HA
    • pCMV3-N-His
    • pCMV3-N-Myc
    • pCMV3-N-OFPSpark
    • pCMV3-untagged
    • pCMV6-AC-GFP
    • pCas-Guide
    • pMD18-T Simple
    • pCMV-SPORT6
    • pCMV6-XL4
    • pCMV6-XL5
    • pLX304
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
    • TA-Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
    • gRNA + gRNA
  • Oligo-Type
    • siRNA Oligo
    • qPCR Primer
  • Resistance Gene
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
    • Zeocin
  • Expression Type
    • Transient
    • Stable
    • Transient,Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
    • Hygromycin
    • Blasticidin
  • Promoter
    • Enhanced CMV Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • SFFV Promoter
    • PGK Promoter
    • mCMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles
    • Glycerol Stock

Synonyms and alternative names related to MAP3K8

  • mitogen-activated protein kinase kinase kinase 8 (MAP3K8)
  • mitogen-activated protein kinase kinase kinase 8 (map3k8)
  • mitogen-activated protein kinase kinase kinase 8 (Map3k8)
  • c-COT
  • COT
  • Cot
  • Cot/Tpl2
  • D17TPL2
  • EST
  • Est
  • ESTF
  • Estf
  • MAP3K8
  • MEKK8
  • Tpl-2
  • TPL2
  • Tpl2

Gene-IDs for different species

GENE ID SPECIES
450384 Pan troglodytes
100018684 Monodelphis domestica
100063602 Equus caballus
100355566 Oryctolagus cuniculus
100385107 Callithrix jacchus
100480593 Ailuropoda melanoleuca
100541097 Meleagris gallopavo
100562883 Anolis carolinensis
100579516 Nomascus leucogenys
420479 Gallus gallus
1326 Homo sapiens
487085 Canis lupus familiaris
535622 Bos taurus
26410 Mus musculus
116596 Rattus norvegicus
449002 Sus scrofa

Protein level used designations for MAP3K8

  • mitogen-activated protein kinase kinase kinase 8
  • Ewing sarcoma transformant
  • cot (cancer Osaka thyroid) oncogene
  • proto-oncogene c-Cot
  • proto-oncogene serine/threoine protein kinase
  • tumor progression locus 2
  • COT proto-oncogene serine/threonine-protein kinase
  • cancer Osaka thyroid oncogene
  • cancer Osaka thyroid, oncogene
  • mitogen activated protein kinase kinase kinase 8
  • serine/threonine-protein kinase cot
  • serine/threonine kinase (Tpl-2)
Other products related to MAP3K8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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