MCFD2 (Multiple Coagulation Factor Deficiency 2, MCFD2)
Short Description: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1\; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D)\; a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010].
More information related to gene MCFD2.
More information related to gene MCFD2.
Products related to MCFD2 Gene:
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82 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Multiple Coagulation Factor Deficiency 2 (MCFD2)
- NCBI Accession:
- NM_001171511
- Gene ID:
- 90411 (Human, MCFD2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4927354
OriGene sr400516
RNAi
MCFD2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Multiple Coagulation Factor Deficiency 2
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3274567
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to MCFD2
- multiple coagulation factor deficiency 2 (MCFD2)
- multiple coagulation factor deficiency 2 (mcfd2)
- multiple coagulation factor deficiency 2 L homeolog (mcfd2.L)
- multiple coagulation factor deficiency 2 (Mcfd2)
- 1810021C21Rik
- DKFZp469B098
- F5F8D
- F5f8d
- F5F8D2
- hm:zeh1186
- LMAN1IP
- Lman1ip
- MCFD2
- SDNSF
- Sdnsf
- wu:fc23b10
- wu:fd50d08
- zgc:103713
- zgc:109915
Gene-IDs for different species
Protein level used designations for MCFD2
- multiple coagulation factor deficiency 2
- multiple coagulation factor deficiency protein 2
- Multiple coagulation factor deficiency protein 2 homolog
- neural stem cell derived neuronal survival protein
- neural stem cell-derived neuronal survival protein
- multiple coagulation factor deficiency protein 2 homolog
- stem cell derived neuronal survival protein
Proteomics products related to MCFD2 Gene
Other products related to MCFD2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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