MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse), MDM2)
Short Description: This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues. [provided by RefSeq, Jul 2008].
More information related to gene MDM2.
More information related to gene MDM2.
Products related to MDM2 Gene:
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72 results
OriGene kn509909
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3242510
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn419518
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3242509
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to MDM2
- MDM2 proto-oncogene (MDM2)
- MDM2 proto-oncogene S homeolog (mdm2.S)
- MDM2 proto-oncogene (Mdm2)
- Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) (MDM2)
- MDM2 oncogene, E3 ubiquitin protein ligase (mdm2)
- transformed mouse 3T3 cell double minute 2 (Mdm2)
- 1700007J15Rik
- AA415488
- ACTFS
- hdm2
- HDMX
- Mdm-2
- zgc:109834
Gene-IDs for different species
Protein level used designations for MDM2
- E3 ubiquitin-protein ligase Mdm2
- Mdm2, p53 E3 ubiquitin protein ligase homolog
- Mdm2, transformed 3T3 cell double minute 2, p53 binding protein
- double minute 2, human homolog of; p53-binding protein
- oncoprotein Mdm2
- Mdm2 p53 binding protein homolog
- double minute 2 protein
- p53-binding protein Mdm2
- xdm2
- MDM2 alpha
- cdm2
- double minute 2 homolog
- double minute 2
- MDM2-like protein
- edm2
- transformed mouse 3T3 cell double minute 2
- etID309863.4
- murine double minute 2 homolog
Proteomics products related to MDM2 Gene
Other products related to MDM2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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