Metabotropic Glutamate Receptor 4 (Glutamate Receptor, Metabotropic 4, GRM4)
Short Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
More information related to gene Metabotropic Glutamate Receptor 4.
More information related to gene Metabotropic Glutamate Receptor 4.
Products related to Metabotropic Glutamate Receptor 4 Gene:
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81 results
OriGene rc234974
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Glutamate Receptor, Metabotropic 4 (GRM4)
- NCBI Accession:
- NM_001256811,NP_001243740
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5355411
$862.29
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10 μg
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Synonyms and alternative names related to Metabotropic Glutamate Receptor 4
- glutamate metabotropic receptor 4 (GRM4)
- glutamate receptor, metabotropic 4 (Grm4)
- glutamate metabotropic receptor 4 (Grm4)
- glutamate receptor, metabotropic 4 (GRM4)
- GPRC1D
- Gprc1d
- mGlu4
- MGLUR4
- mGluR4
Gene-IDs for different species
Protein level used designations for Metabotropic Glutamate Receptor 4
- metabotropic glutamate receptor 4
- G protein-coupled receptor GRM4
- G protein-coupled receptor, family C, group 1, member D
- mGluR4
Proteomics products related to Metabotropic Glutamate Receptor 4 Gene
Other products related to Metabotropic Glutamate Receptor 4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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