MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1, MLL1)
Short Description: Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).
More information related to gene MLL1.
More information related to gene MLL1.
Products related to MLL1 Gene:
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16 results
OriGene tg517798
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3699764
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tf517798
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3680065
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr517798
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3550773
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tl517798
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3530365
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr507022
RNAi
MLL1
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- Myeloid/lymphoid Or Mixed-Lineage Leukemia 1
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3356563
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr423671
RNAi
MLL1
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Myeloid/lymphoid Or Mixed-Lineage Leukemia 1
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3350509
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to MLL1
- lysine methyltransferase 2A (Kmt2a)
- lysine (K)-specific methyltransferase 2A (Kmt2a)
- 6430520K01
- ALL-1
- All1
- Cxxc7
- HRX
- HTRX1
- mKIAA4050
- Mll
- Mll1
Gene-IDs for different species
Protein level used designations for MLL1
- Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene)
- histone-lysine N-methyltransferase MLL
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
- myeloid/lymphoid or mixed-lineage leukemia 1
- histone-lysine N-methyltransferase 2A
- lysine N-methyltransferase 2A
- myeloid/lymphoid or mixed-lineage leukemia protein 1
- trithorax Drosophila
- zinc finger protein HRX
Proteomics products related to MLL1 Gene
Other products related to MLL1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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