NCF4 (Neutrophil Cytosolic Factor 4, 40kDa, NCF4)
Short Description: The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
More information related to gene NCF4.
More information related to gene NCF4.
Products related to NCF4 Gene:
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64 results
OriGene sr303088
RNAi
NCF4
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Neutrophil Cytosolic Factor 4, 40kDa
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342868
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rr205963
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Neutrophil Cytosolic Factor 4, 40kDa (NCF4)
- NCBI Accession:
- NM_001127304,NP_001120776
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5384249
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Neutrophil Cytosolic Factor 4, 40kDa (NCF4)
- NCBI Accession:
- NM_000631
- Gene ID:
- 4689 (Human, NCF4)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4926763
$319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Neutrophil Cytosolic Factor 4, 40kDa (NCF4)
- NCBI Accession:
- NM_013416
- Gene ID:
- 4689 (Human, NCF4)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4926762
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
Synonyms and alternative names related to NCF4
- neutrophil cytosolic factor 4 (ncf4)
- neutrophil cytosolic factor 4 (Ncf4)
- neutrophil cytosolic factor 4 (NCF4)
- AI451400
- NCF
- p40phox
- P40PHOX
- SH3PXD4
Gene-IDs for different species
Protein level used designations for NCF4
- p40phox protein
- neutrophil cytosolic factor 4
- NADPH oxidase cytosolic protein p40phox
- NCF-4
- neutrophil NADPH oxidase factor 4
- neutrophil cytosol factor 4
- p40-phox
- SH3 and PX domain-containing protein 4
Proteomics products related to NCF4 Gene
Other products related to NCF4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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