NCOA2 (Nuclear Receptor Coactivator 2, NCOA2)
Short Description: The NCOA2 gene encodes nuclear receptor coactivator 2, which aids in the function of nuclear hormone receptors. Nuclear hormone receptors are conditional transcription factors that play important roles in various aspects of cell growth, development, and homeostasis by controlling expression of specific genes. Members of the nuclear hormone receptor superfamily, which includes the 5 steroid receptors and class II nuclear receptors (see below), are structurally characterized by 3 distinct domains: an N-terminal transcriptional activation domain, a central DNA-binding domain, and a C-terminal hormone-binding domain. Before the binding of hormone, steroid receptors, which are sometimes called class I of the nuclear hormone receptor family, remain inactive in a complex with heat-shock protein-90 (MIM 140571) and other stress family proteins. Binding of hormone induces critical conformational changes in steroid receptors that cause them to dissociate from the inhibitory complex, bind as homodimers to specific DNA enhancer elements associated with target genes, and modulate that gene's transcription. After binding to enhancer elements, transcription factors require transcriptional coactivator proteins to mediate their stimulation of transcription initiation (Hong et al., 1997 [PubMed 9111344]).[supplied by OMIM, Nov 2010].
More information related to gene NCOA2.
More information related to gene NCOA2.
Products related to NCOA2 Gene:
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65 results
OriGene rc212235l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Nuclear Receptor Coactivator 2 (NCOA2)
- NCBI Accession:
- NM_006540,NP_006531
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5386577
$2,156.22
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc212235l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Nuclear Receptor Coactivator 2 (NCOA2)
- NCBI Accession:
- NM_006540,NP_006531
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5386576
$2,156.22
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc316986
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL6
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Nuclear Receptor Coactivator 2 (NCOA2)
- NCBI Accession:
- NM_006540,NP_006531
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL6
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, SP6 Promoter
- Expression:
- Transient
Catalog No. ABIN3394043
$1,860.21
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Nuclear Receptor Coactivator 2 (NCOA2)
- NCBI Accession:
- NM_006540
- Gene ID:
- 10499 (Human, NCOA2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4946775
$549.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 26 to 27 Business Days
OriGene sr307135
RNAi
NCOA2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Nuclear Receptor Coactivator 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3346889
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to NCOA2
- nuclear receptor coactivator 2 (NCOA2)
- nuclear receptor coactivator 2 (Ncoa2)
- nuclear receptor coactivator 2 (ncoa2)
- nuclear receptor coactivator 2 (LOC100089041)
- nuclear receptor coactivator 2 S homeolog (ncoa2.S)
- 9530095N19
- bHLHe75
- bhlhe75
- D1Ertd433e
- GRIP-1
- GRIP1
- Grip1
- grip1
- KAT13C
- kat13c
- NCoA-2
- NCOA2
- ncoa2-A
- SRC-2
- SRC2
- src2
- TIF-2
- TIF2
- tif2
- Tif2
- wu:fc41a10
- wu:fe26a11
- XTIF2
Gene-IDs for different species
Protein level used designations for NCOA2
- class E basic helix-loop-helix protein 75
- glucocorticoid receptor-interacting protein-1
- hTIF2
- transcriptional intermediary factor 2
- NCoA-2
- TIF2/GRIP-1
- glucocorticoid receptor interacting protein 1
- glucocorticoid receptor-interacting protein 1
- grip1
- src2
- steroid receptor coactivator 2
- nuclear receptor coactivator 2
- transcriptional intermediary factor-2
- Transcriptional intermediary factor 2
- nuclear receptor coactivator 2-like
Proteomics products related to NCOA2 Gene
Other products related to NCOA2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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