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NEDD4-2 (E3 ubiquitin-protein ligase NEDD4-like, NEDD4L)

Short Description: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
More information related to gene NEDD4-2.

Products related to NEDD4-2 Gene:

81 results

OriGene rr206542 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001008300,NP_001008301
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5347864
$960.30
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene rc226655 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L)
NCBI Accession:
NM_001144970,NP_001138442
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5347861
$831.60
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene rc226659 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L)
NCBI Accession:
NM_001144971,NP_001138443
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5347862
$831.60
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001144971
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943175
$839.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001144968
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943177
$939.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_015277
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943178
$939.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001144964
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943174
$679.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001243960
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943179
$679.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001144969
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943176
$939.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001144967
Gene ID:
23327 (Human, NEDD4L)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4943180
$679.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to NEDD4-2

  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L)
  • NEDD4L (LOC776799)
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog (nedd4l.S)
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (Nedd4l)
  • neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l)
  • 1300012C07Rik
  • hNEDD4-2
  • nedd4
  • NEDD4
  • NEDD4-2
  • nedd4-2
  • Nedd4-2
  • NEDD4.2
  • Nedd4b
  • RSP5

Gene-IDs for different species

Protein level used designations for NEDD4-2

  • E3 ubiquitin-protein ligase NEDD4-like
  • E3 ubiquitin-protein ligase NEDD4-like protein
  • ubiquitin-protein ligase Rsp5
  • neural precursor cell expressed, developmentally down-regulated 4
  • NEDD4.2
  • neural precursor cell expressed, developmentally down-regulated gene 4b
Other products related to NEDD4-2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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