NEDD4-2 (E3 ubiquitin-protein ligase NEDD4-like, NEDD4L)
Short Description: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
More information related to gene NEDD4-2.
More information related to gene NEDD4-2.
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OriGene sr308189
RNAi
NEDD4L
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- E3 ubiquitin-protein ligase NEDD4-like
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3284228
$512.82
Plus shipping costs $50.00
1 kit
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United States
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Synonyms and alternative names related to NEDD4-2
- neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L)
- NEDD4L (LOC776799)
- neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog (nedd4l.S)
- neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (Nedd4l)
- neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l)
- 1300012C07Rik
- hNEDD4-2
- nedd4
- NEDD4
- NEDD4-2
- nedd4-2
- Nedd4-2
- NEDD4.2
- Nedd4b
- RSP5
Gene-IDs for different species
Protein level used designations for NEDD4-2
- E3 ubiquitin-protein ligase NEDD4-like
- E3 ubiquitin-protein ligase NEDD4-like protein
- ubiquitin-protein ligase Rsp5
- neural precursor cell expressed, developmentally down-regulated 4
- NEDD4.2
- neural precursor cell expressed, developmentally down-regulated gene 4b
Proteomics products related to NEDD4-2 Gene
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