genomics-online.com Logo
Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

NEDD4 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase, NEDD4)

Short Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Involved in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19193720). Predominantly involved in ubiquitination of membrane bound forms of ERBB4 rather than processed precursors and intermediate membrane-anchored 80 kDa fragments (m80HER4), with a lesser role in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19047365). Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2 (By similarity).
More information related to gene NEDD4.

Products related to NEDD4 Gene:

Show Filters

78 results

Rat NEDD4 siRNA Oligo
OriGene sr513927 RNAi NEDD4 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3315477
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse NEDD4 shRNA in Lentiviral Vector (GFP tag)
OriGene tl514761 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3527354
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse NEDD4 siRNA Oligo
OriGene sr420988 RNAi NEDD4 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3347856
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse NEDD4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc222415 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_010890,NP_035020
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3332069
$1,206.81
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human NEDD4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc337996 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_001284340,NP_001271269
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3332071
$1,234.53
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Rat NEDD4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rn214217 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_012986,NP_037118
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3332070
$887.04
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
Details
Details
Human NEDD4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc338000 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_001284338,NP_001271267
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3332073
$1,251.36
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Human NEDD4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc337997 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_001284339,NP_001271268
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3332072
$1,235.52
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Human NEDD4 cDNA Clone in Mammalian Expression Vector
OriGene sc310054 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_006154,NP_006145
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3391075
$816.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human NEDD4 cDNA Clone in Mammalian Expression Vector
OriGene sc123396 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4)
NCBI Accession:
NM_198400,NP_940682
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3391074
$1,075.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pCas-Guide
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to NEDD4

  • neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (NEDD4)
  • neural precursor cell expressed, developmentally down-regulated 4 (Nedd4)
  • CG42279 gene product from transcript CG42279-RJ (Nedd4)
  • E3 ubiquitin-protein ligase Nedd-4 (LOC411723)
  • E3 ubiquitin-protein ligase NEDD4 (LOC100457150)
  • neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (nedd4)
  • E3 ubiquitin-protein ligase NEDD4 (LOC100547485)
  • neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (Nedd4)
  • AA959633
  • AL023035
  • AU019897
  • CG7555
  • CG32184
  • CG42279
  • Dmel\\CG42279
  • Dmel_CG7555
  • Dmel_CG32184
  • DNedd4
  • dNedd4
  • dNedd4-1
  • E430025J12Rik
  • GB16853
  • mKIAA0093
  • nedd4
  • NEDD4
  • Nedd4
  • NEDD4-1
  • Nedd4-1
  • Nedd4a
  • RPF1

Gene-IDs for different species

Protein level used designations for NEDD4

  • E3 ubiquitin-protein ligase NEDD4
  • NEDD-4
  • cell proliferation-inducing gene 53 protein
  • neural precursor cell expressed developmentally down-regulated protein 4
  • receptor-potentiating factor 1
  • neural precursor cell expressed, developmentally down-regulated gene 4
  • neural precursor cell expressed, developmentally down-regulated gene 4a
  • neural precursor cell expressed, developmentally down-regulted gene 4
  • CG42279-PE
  • CG42279-PF
  • CG42279-PG
  • CG42279-PH
  • CG42279-PI
  • CG42279-PJ
  • CG42279-PK
  • CG42279-PL
  • CG42279-PM
  • DNedd4
  • Nedd4-PE
  • Nedd4-PF
  • Nedd4-PG
  • Nedd4-PH
  • Nedd4-PI
  • Nedd4-PJ
  • Nedd4-PK
  • Nedd4-PL
  • Nedd4-PM
  • neural precursor cell expressed, developmentally down-regulated 4
  • ubiquitin-protein ligase Nedd4
  • E3 ubiquitin-protein ligase NEDD4-like
  • e3 ubiquitin-protein ligase NEDD4-like
  • neural precursor cell expressed, developmentally down-regulated gene 4A
Other products related to NEDD4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
antibodies-online
german

german (deutsch) antikoerper-online.de

english

english (english) antibodies-online.com

french

french (français) anticorps-enligne.fr

chinese

chinese (中文) antibodies-online.cn

genomics-online
english

english (english) genomics-online.com