NLRP3 (NLR Family, Pyrin Domain Containing 3, NLRP3)
Short Description: This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq, Oct 2008].
More information related to gene NLRP3.
More information related to gene NLRP3.
Products related to NLRP3 Gene:
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76 results
OriGene rg226286
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5342018
$1,528.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg226287
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5342019
$1,528.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rc220952
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_004895,NP_004886
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342022
$892.98
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc223212
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_183395,NP_899632
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342023
$583.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rc226287
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_001127462,NP_001120934
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342025
$1,330.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg235131
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5342020
$1,178.10
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene rc213623
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_001079821,NP_001073289
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342021
$892.98
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc235131
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_001243133,NP_001230062
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342026
$980.10
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene rc226286
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_001127461,NP_001120933
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342024
$1,330.56
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc220952l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_004895,NP_004886
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5342034
$1,189.98
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
Synonyms and alternative names related to NLRP3
- NLR family pyrin domain containing-like (NLRPL)
- NLR family pyrin domain containing 3 (NLRP3)
- NLR family, pyrin domain containing 3 L homeolog (nlrp3.L)
- NLR family, pyrin domain containing 3 (Nlrp3)
- agtavprl
- AGTAVPRL
- AII
- AII/AVP
- avp
- AVP
- C1orf7
- CIAS1
- cias1
- Cias1
- CLR1.1
- FCAS
- FCU
- Mmig1
- MWS
- Nalp3
- nalp3
- NALP3
- pypaf1
- PYPAF1
- Pypaf1
Gene-IDs for different species
Protein level used designations for NLRP3
- NACHT, LRR and PYD domains-containing protein 3
- cold autoinflammatory syndrome 1
- cryopyrin
- NLR family, pyrin domain containing 3
- NACHT, LRR and PYD domains-containing protein 3-like
- NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3
- NACHT, LRR and PYD containing protein 3
- PYRIN-containing APAF1-like protein 1
- caterpiller protein 1.1
- cold autoinflammatory syndrome 1 protein
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
- NACHT/LRR/pyrin domain-containing protein 3
- cold autoinflammatory syndrome 1 homolog
- cold autoinflammatory syndrome 1 protein homolog
- mast cell maturation inducible protein 1
- mast cell maturation-associated-inducible protein 1
- NLR family pyrin domain containing 3
Proteomics products related to NLRP3 Gene
Other products related to NLRP3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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