NLRP3 (NLR Family, Pyrin Domain Containing 3, NLRP3)
Short Description: This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq, Oct 2008].
More information related to gene NLRP3.
More information related to gene NLRP3.
Products related to NLRP3 Gene:
Recommended next Filters:
76 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_183395
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_001191642
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_145827
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- NLR Family, Pyrin Domain Containing 3 (NLRP3)
- NCBI Accession:
- NM_001191642
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Synonyms and alternative names related to NLRP3
- NLR family pyrin domain containing-like (NLRPL)
- NLR family pyrin domain containing 3 (NLRP3)
- NLR family, pyrin domain containing 3 L homeolog (nlrp3.L)
- NLR family, pyrin domain containing 3 (Nlrp3)
- agtavprl
- AGTAVPRL
- AII
- AII/AVP
- avp
- AVP
- C1orf7
- CIAS1
- cias1
- Cias1
- CLR1.1
- FCAS
- FCU
- Mmig1
- MWS
- Nalp3
- nalp3
- NALP3
- pypaf1
- PYPAF1
- Pypaf1
Gene-IDs for different species
Protein level used designations for NLRP3
- NACHT, LRR and PYD domains-containing protein 3
- cold autoinflammatory syndrome 1
- cryopyrin
- NLR family, pyrin domain containing 3
- NACHT, LRR and PYD domains-containing protein 3-like
- NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3
- NACHT, LRR and PYD containing protein 3
- PYRIN-containing APAF1-like protein 1
- caterpiller protein 1.1
- cold autoinflammatory syndrome 1 protein
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
- NACHT/LRR/pyrin domain-containing protein 3
- cold autoinflammatory syndrome 1 homolog
- cold autoinflammatory syndrome 1 protein homolog
- mast cell maturation inducible protein 1
- mast cell maturation-associated-inducible protein 1
- NLR family pyrin domain containing 3
Proteomics products related to NLRP3 Gene
Other products related to NLRP3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
