NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1, NUB1)
Short Description: This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].
More information related to gene NUB1.
More information related to gene NUB1.
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OriGene sr309907
RNAi
NUB1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Negative Regulator of Ubiquitin-Like Proteins 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3285943
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to NUB1
- negative regulator of ubiquitin-like proteins 1 (Nub1)
- negative regulator of ubiquitin like proteins 1 (NUB1)
- 4931404D21Rik
- 6330412F12Rik
- BS4
- NUB1L
- NY-REN-18
- NYREN18
Gene-IDs for different species
Protein level used designations for NUB1
- NEDD8 ultimate buster 1
- NEDD8 ultimate buster-1
- NY-REN-18 antigen
- renal carcinoma antigen NY-REN-18
- Nedd8 ultimate buster-1
Proteomics products related to NUB1 Gene
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