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Patched 1 (Patched 1, PTCH1)

Short Description: This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008].
More information related to gene Patched 1.

Products related to Patched 1 Gene:

73 results

OriGene rc220617 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Patched 1 (PTCH1)
NCBI Accession:
NM_001083603,NP_001077072
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5406782
$1,346.40
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
OriGene rc220660 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Patched 1 (PTCH1)
NCBI Accession:
NM_001083606,NP_001077075
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5406783
$1,228.59
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene sr303859 RNAi PTCH1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Patched 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3343633
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pPB-His-GST
    • pPB-His-MBP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL5
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Patched 1

  • patched 1 (PTCH1)
  • patched 1 (ptch1)
  • patched 1 (Ptch1)
  • patched 1 L homeolog (ptch1.L)
  • Protein patched homolog 1 (ptc-1)
  • A230106A15Rik
  • BCNS
  • HPE7
  • lep
  • mes
  • NBCCS
  • patched
  • patched1
  • PTC
  • Ptc
  • Ptc-1
  • PTC1
  • ptc1
  • Ptc1
  • ptc2
  • PTCH
  • Ptch
  • Ptch2
  • PTCH11
  • XPtc1

Gene-IDs for different species

Protein level used designations for Patched 1

  • PTCH protein +12b
  • PTCH protein +4'
  • PTCH protein -10
  • PTCH protein -3,4,5
  • protein patched homolog 1
  • leprechaun
  • patched 2
  • patched homolog 2
  • patched homolog 1
  • patched-1
  • patched 1
  • patched-like
  • protein patched homolog 1-like
  • Patched 1
  • Ptch1 protein +12b
  • mesenchymal dysplasia
  • PTC1
  • patched protein
  • patched-like protein
  • LOW QUALITY PROTEIN: protein patched homolog 1
Other products related to Patched 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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