PDGFB (Platelet Derived Growth Factor Subunit B, PDGFB)
Short Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013].
More information related to gene PDGFB.
More information related to gene PDGFB.
Products related to PDGFB Gene:
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OriGene rc206587l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Platelet-Derived Growth Factor beta Polypeptide (PDGFB)
- NCBI Accession:
- NM_002608,NP_002599
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5454349
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg222432
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Platelet Derived Growth Factor Subunit B (PDGFB)
- NCBI Accession:
- NM_033016,NP_148937
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5454346
$495.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc222432
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Platelet-Derived Growth Factor beta Polypeptide (PDGFB)
- NCBI Accession:
- NM_033016,NP_148937
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5454348
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr303420
RNAi
PDGFB
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Platelet Derived Growth Factor Subunit B
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343198
$435.60
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to PDGFB
- platelet derived growth factor subunit B (PDGFB)
- platelet-derived growth factor beta polypeptide (PDGFB)
- platelet derived growth factor subunit B S homeolog (pdgfb.S)
- platelet-derived growth factor beta polypeptide a (pdgfba)
- platelet derived growth factor, B polypeptide (Pdgfb)
- platelet derived growth factor subunit B (Pdgfb)
- c-sis
- PDGF-2
- PDGF-B
- PDGF2
- pdgf2
- si:ch211-79m20.1
- si:dkey-261d11.1
- SIS
- sis
- Sis
- SSV
Gene-IDs for different species
Protein level used designations for PDGFB
- PDGF subunit B
- PDGF, B chain
- becaplermin
- platelet-derived growth factor 2
- platelet-derived growth factor B chain
- platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
- platelet-derived growth factor subunit B
- platelet-derived growth factor, beta polypeptide (oncogene SIS)
- proto-oncogene c-Sis
- platelet-derived growth factor B
- v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)
- PDGF-2
- c-sis
- platelet-derived growth factor beta polypeptide
- Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis)
- pdgf protein
- platelet derived growth factor, B polypeptide
- platelet-derived growth factor B subunit
- Platelet-derived growth factor B chain
Proteomics products related to PDGFB Gene
Other products related to PDGFB such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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