Phospholamban (Phospholamban, PLN)
Short Description: The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].
More information related to gene Phospholamban.
More information related to gene Phospholamban.
Products related to Phospholamban Gene:
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63 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Phospholamban (PLN)
- NCBI Accession:
- NM_002667
- Gene ID:
- 5350 (Human, PLN)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4936534
OriGene sr400103
RNAi
PLN
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Phospholamban
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3274164
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr303574
RNAi
PLN
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Phospholamban
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343351
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to Phospholamban
- phospholamban (PLN)
- phospholamban (pln)
- phospholamban (Pln)
- cmd1p
- CMD1P
- CMH18
- LOC100226261
- plb
- PLB
- Plb
- Plm
Gene-IDs for different species
Protein level used designations for Phospholamban
- phospholamban
- cardiac phospholamban
- PLB
Proteomics products related to Phospholamban Gene
Other products related to Phospholamban such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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