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PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing, PIKFYVE)

Short Description: Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve\; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD)\; an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].
More information related to gene PIKFYVE.

Products related to PIKFYVE Gene:

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43 results

Human PIKFYVE cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc313536 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_152671,NP_689884
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322722
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PIKFYVE cDNA Clone in Mammalian Expression Vector
OriGene sc121037 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_015040,NP_055855
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3379409
$1,714.68
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse PIKFYVE cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc225150 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_011086,NP_035216
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3364506
$1,845.36
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 61 to 62 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_015040
Gene ID:
200576 (Human, PIKFYVE)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4917124
$1,319.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_152671
Gene ID:
200576 (Human, PIKFYVE)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4936606
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_001178000
Gene ID:
200576 (Human, PIKFYVE)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925475
$459.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg212288 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5454660
$650.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg222618 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5454661
$2,082.96
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 61 to 62 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg230258 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5454662
$702.90
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PIKFYVE ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc212288 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE)
NCBI Accession:
NM_152671,NP_689884
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5454663
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-XL4
    • pDONR223
    • pPB-His-GST
    • pPB-His-MBP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PIKFYVE

  • phosphoinositide kinase, FYVE finger containing (pikfyve)
  • phosphoinositide kinase, FYVE-type zinc finger containing (PIKFYVE)
  • phosphoinositide kinase, FYVE type zinc finger containing (Pikfyve)
  • phosphoinositide kinase, FYVE-type zinc finger containing (Pikfyve)
  • 5230400C17Rik
  • CFD
  • FAB1
  • fab1-like
  • p235
  • PIP5K
  • Pip5k
  • pip5k3
  • PIP5K3
  • Pip5k3
  • Pipk5k3
  • PipkIII
  • wu:fo93c03
  • ZFYVE29

Gene-IDs for different species

Protein level used designations for PIKFYVE

  • 1-phosphatidylinositol-3-phosphate 5-kinase
  • phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
  • 1-phosphatidylinositol 3-phosphate 5-kinase
  • PIPkin-III
  • phosphatidylinositol 3-phosphate 5-kinase type III
  • type III PIP kinase
  • zinc finger, FYVE domain containing 29
  • FYVE finger-containing phosphoinositide kinase
  • PtdIns(4)P-5-kinase
  • phosphatidylinositol-3-phosphate 5-kinase type III
  • phosphatidylinositol-4-phosphate 5-kinase, type III
Other products related to PIKFYVE such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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