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PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1), PRKAR1A)

Short Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed. [provided by RefSeq, Jan 2013].
More information related to gene PRKAR1A.

Products related to PRKAR1A Gene:

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70 results

Human PRKAR1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc212810 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
NCBI Accession:
NM_212472,NP_997637
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5412669
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc210623 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
NCBI Accession:
NM_212471,NP_997636
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5412668
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc237552 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5412671
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc237864 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5412672
$286.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg203828 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5412663
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg212810 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5412665
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg232622 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5412666
$650.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg210623 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5412664
$650.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PRKAR1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc203828 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A)
NCBI Accession:
NM_002734,NP_002725
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5412667
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKAR1A siRNA Oligo
OriGene sr303731 RNAi PRKAR1A Species: Human HPLC purified
Application:
RNA Interference
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1)
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3343506
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PRKAR1A

  • protein kinase cAMP-dependent type I regulatory subunit alpha (PRKAR1A)
  • protein kinase, cAMP dependent regulatory, type I, alpha (Prkar1a)
  • protein kinase cAMP-dependent type 1 regulatory subunit alpha (Prkar1a)
  • protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a (prkar1aa)
  • cAMP-dependent protein kinase type I-alpha regulatory subunit pseudogene (LOC707275)
  • protein kinase cAMP-dependent type I regulatory subunit alpha (Prkar1a)
  • protein kinase cAMP-dependent type I regulatory subunit alpha S homeolog (prkar1a.S)
  • 1300018C22Rik
  • ACRDYS1
  • ADOHR
  • CAR
  • CNC
  • CNC1
  • cnc1
  • im:7047729
  • PKR1
  • pkr1
  • PPNAD1
  • ppnad1
  • PRKAR1
  • prkar1
  • prkar1a
  • RIalpha
  • RIIA
  • Tse-1
  • TSE1
  • Tse1
  • tse1
  • zgc:92515

Gene-IDs for different species

Protein level used designations for PRKAR1A

  • cAMP-dependent protein kinase regulatory subunit RIalpha
  • cAMP-dependent protein kinase type I-alpha regulatory chain
  • cAMP-dependent protein kinase type I-alpha regulatory subunit
  • protein kinase A type 1a regulatory subunit
  • tissue-specific extinguisher 1
  • protein kinase, cAMP dependent regulatory, type 1, alpha
  • protein kinase, cAMP dependent regulatory, type I, alpha
  • cAMP-dependent protein kinase type I regulatory subunit
  • protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
  • cAMP-dependent protein kinase, regulatory subunit alpha 1
  • cAMP-dependent protein kinase regulatory subunit alpha 1
  • cAMP-dependent protein kinase type I-alpha regulatory subunit-like
  • protein kinase, cAMP-dependent, regulatory subunit type I alpha S homeolog
Other products related to PRKAR1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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