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PRKG1 (Protein Kinase, CGMP-Dependent, Type I, PRKG1)

Short Description: Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity. [provided by RefSeq, Sep 2011].
More information related to gene PRKG1.

Products related to PRKG1 Gene:

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66 results

Human PRKG1 cDNA Clone in Mammalian Expression Vector
OriGene sc316416 cDNA PExp Mammalian Expression Vector pCMV6-Neo Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001098512,NP_001091982
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3376660
$608.85
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse PRKG1 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc220322 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001013833,NP_001013855
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3365749
$608.85
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse PRKG1 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc220418 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_011160,NP_035290
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3365750
$685.08
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
Details
Details
Rat PRKG1 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rn208372 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001105731,NP_001099201
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3365751
$670.23
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
Details
Details
Human PRKG1 cDNA Clone in Mammalian Expression Vector
OriGene sc116252 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258,NP_006249
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3381686
$622.71
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human PRKG1 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_001098512
Gene ID:
5592 (Human, PRKG1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4942743
$679.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Human PRKG1 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258
Gene ID:
5592 (Human, PRKG1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4936298
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Details
Details
Human PRKG1 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc220986 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258,NP_006249
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5396462
$621.72
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKG1 ORF Clone in Lentiviral Vector (Myc-DYKDDDDK Tag)
OriGene rc220986l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258,NP_006249
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5396466
$918.72
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PRKG1 ORF Clone in Lentiviral Vector (GFP tag)
OriGene rc220986l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CGMP-Dependent, Type I (PRKG1)
NCBI Accession:
NM_006258,NP_006249
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5396464
$918.72
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-Neo
    • pCMV6-XL4
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PRKG1

  • protein kinase, cGMP-dependent, type Ia (prkg1a)
  • protein kinase, cGMP-dependent, type I (PRKG1)
  • protein kinase, cGMP-dependent, type I (prkg1)
  • protein kinase, cGMP-dependent, type 1 (Prkg1)
  • protein kinase, cGMP-dependent, type I (Prkg1)
  • 1
  • AW125416
  • cGK
  • cGk1
  • cGK 1
  • cGK1
  • cGKI
  • CGKI
  • cGKI-alpha
  • cGKI-BETA
  • cGKI-beta
  • Gm19690
  • PKG
  • Pkgi
  • prkg1
  • PRKG1B
  • Prkg1b
  • Prkg1beta
  • PRKGR1B
  • Prkgr1b
  • zgc:63955

Gene-IDs for different species

Protein level used designations for PRKG1

  • cGMP-dependent protein kinase 1
  • protein kinase, cGMP-dependent, type I
  • cGMP-dependent protein kinase 1, beta isozyme
  • cGMP-dependent protein kinase I alpha
  • cGK I alpha
  • cGMP-dependent protein kinase 1-like
  • cGMP dependent protein kinase type 1
  • protein kinase, cGMP-dependent, regulatory, type I, beta
  • CGK 1 alpha
  • cGK 1 beta
  • cGK1
  • cGKI-alpha
  • cGMP-dependent protein kinase 1, alpha isozyme
  • cGMP-dependent protein kinase I
  • cGK 1
  • PKG1 alpha
  • cGMP-dependent protein kinase type 1 alpha
  • cGMP-dependent protein kinase type I beta
Other products related to PRKG1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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