PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta), PSME2)
Short Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. [provided by RefSeq, Jul 2008].
More information related to gene PSME2.
More information related to gene PSME2.
Products related to PSME2 Gene:
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ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5315734
$204.05
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2 μg
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Synonyms and alternative names related to PSME2
- proteasome activator subunit 2 (psme2)
- proteasome activator subunit 2 (PSME2)
- proteasome activator subunit 2 (Psme2)
- proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (Psme2)
- AA589371
- AI788882
- PA28B
- PA28b
- PA28beta
- REGbeta
- unp309
Gene-IDs for different species
Protein level used designations for PSME2
- proteasome activator complex subunit 2
- pA28-b
- proteasome activator subunit 2
- 11S regulator complex subunit beta
- PA28b
- PA28beta
- REG-beta
- activator of multicatalytic protease subunit 2
- protease (prosome, macropain) 28 subunit, beta
- proteasome (prosome, macropain) 28 subunit, beta
- proteasome activator 28 subunit beta
- 11S regulator complex beta subunit
- MCP activator, 31-kD subunit
- cell migration-inducing protein 22
- proteasome activator 28-beta
- proteasome activator hPA28 subunit beta
- PA28 beta subunit
- proteasome activator 28 beta subunit
Proteomics products related to PSME2 Gene
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