PTEN (Phosphatase and Tensin Homolog, PTEN)
Short Description: This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway. [provided by RefSeq, Jul 2008].
More information related to gene PTEN.
More information related to gene PTEN.
Products related to PTEN Gene:
Recommended next Filters:
1 results :
RNAi
PTEN
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Phosphatase and Tensin Homolog
- Species:
- Mouse
- Purification:
- HPLC purified
Synonyms and alternative names related to PTEN
- phosphatase and tensin homolog (PTEN)
- phosphatase and tensin homolog (Pten)
- phosphatase and tensin homolog L homeolog (pten.L)
- phosphatase and tensin homolog A (ptena)
- phosphatase and tensin homolog B (ptenb)
- 10q23del
- 2310035O07Rik
- A130070J02Rik
- AI463227
- B430203M17Rik
- BZS
- CWS1
- DEC
- fa11a08
- fb73f10
- fc83f12
- fd16b10
- fk90e11
- GLM2
- MHAM
- Mmac
- MMAC1
- pten
- PTEN1
- PTENP1
- si:bz1g13.4
- TEP1
- wu:fa11a08
- wu:fb73f10
- wu:fc52g04
- wu:fc83f12
- wu:fd16b10
- wu:fk90e11
- zgc:73086
Gene-IDs for different species
Protein level used designations for PTEN
- MMAC1 phosphatase and tensin homolog deleted on chromosome 10
- mutated in multiple advanced cancers 1
- phosphatase and tensin-like protein
- phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
- protein tyrosine phosphatase and tensin-like protein
- phosphatase and tensin homolog deleted on chromosome ten
- protein/lipid phosphatase Pten
- homolog of human mutated in multiple advanced cancers
- phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
- phosphatase and tensin homolog A
- phosphatase and tensin-like protein A
- phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)
Proteomics products related to PTEN Gene
Other products related to PTEN such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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