PTPN12 (Protein Tyrosine Phosphatase G1, PTPN12)
Short Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
More information related to gene PTPN12.
More information related to gene PTPN12.
Products related to PTPN12 Gene:
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OriGene sr303893
RNAi
PTPN12
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Protein Tyrosine Phosphatase G1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343667
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
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Synonyms and alternative names related to PTPN12
- protein tyrosine phosphatase, non-receptor type 12 (PTPN12)
- protein tyrosine phosphatase, non-receptor type 12 (Ptpn12)
- P19-PTP
- PTP-P19
- PTP-PEST
- PTPG1
- Ptpg1
- RKPTP
Gene-IDs for different species
Protein level used designations for PTPN12
- protein-tyrosine phosphatase G1
- tyrosine-protein phosphatase non-receptor type 12
- MPTP-PEST
- protein-tyrosine phosphatase P19
Proteomics products related to PTPN12 Gene
Other products related to PTPN12 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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