PTTG1 (Pituitary Tumor-Transforming 1, PTTG1)
Short Description: The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. [provided by RefSeq, Jul 2008].
More information related to gene PTTG1.
More information related to gene PTTG1.
Products related to PTTG1 Gene:
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62 results
OriGene rc211038l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Pituitary Tumor-Transforming 1 (PTTG1)
- NCBI Accession:
- NM_004219,NP_004210
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5406738
$742.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr306112
RNAi
PTTG1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Pituitary Tumor-Transforming 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3345874
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to PTTG1
- pituitary tumor-transforming 1 (PTTG1)
- pituitary tumor-transforming gene 1 (Pttg1)
- pituitary tumor-transforming 1 (Pttg1)
- securin, sister chromatid separation inhibitor (cut2)
- AW555095
- C87862
- EAP1
- HPTTG
- Protein Cut2
- PTTG
- Pttg
- PTTG1
- Pttg3
- securin
- Securin
- TUTR1
Gene-IDs for different species
Protein level used designations for PTTG1
- ESP1-associated protein 1
- pituitary tumor-transforming gene 1 protein
- securin
- tumor-transforming protein 1
- pituitary tumor-transforming protein 1
- pituitary tumor-transforming 1
- Pituitary tumor transforming
- Pituitary tumor-transforming gene 1 protein
- Cell untimely torn protein 2
Proteomics products related to PTTG1 Gene
Other products related to PTTG1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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