PUMA (BCL2 Binding Component 3, BBC3)
Short Description: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011].
More information related to gene PUMA.
More information related to gene PUMA.
Products related to PUMA Gene:
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74 results
OriGene rc213203l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- BCL2 Binding Component 3 (BBC3)
- NCBI Accession:
- NM_014417,NP_055232
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5339493
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc225345l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- BCL2 Binding Component 3 (BBC3)
- NCBI Accession:
- NM_001127240,NP_001120712
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5339496
$594.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr404867
RNAi
BBC3
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- BCL2 Binding Component 3
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3278855
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr308982
RNAi
BBC3
Species: Human
HPLC purified
1
- Application:
- RNA Interference
- Gene:
- BCL2 Binding Component 3
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3285019
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to PUMA
- BCL2 binding component 3 (BBC3)
- Bcl-2 binding component 3 (Bbc3)
- BCL2 binding component 3 (Bbc3)
- BCL2 binding component 3 (bbc3)
- BBC3
- JFY-1
- JFY1
- Puma
- PUMA
- PUMA/JFY1
Gene-IDs for different species
Protein level used designations for PUMA
- BCL2 binding component 3
- bcl-2-binding component 3
- p53 up-regulated modulator of apoptosis
- BH3-only
- Bcl-2 binding component 3
- Puma
Proteomics products related to PUMA Gene
Other products related to PUMA such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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