RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1, RAF1)
Short Description: This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].
More information related to gene RAF1.
More information related to gene RAF1.
Products related to RAF1 Gene:
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OriGene rc201983l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
- NCBI Accession:
- NM_002880,NP_002871
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5394500
$893.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc201983l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
- NCBI Accession:
- NM_002880,NP_002871
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5394499
$893.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
- NCBI Accession:
- NM_002880
- Gene ID:
- 5894 (Human, RAF1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4936042
$379.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rr200564
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
- NCBI Accession:
- NM_012639,NP_036771
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5335529
$656.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr303972
RNAi
RAF1
Species: Human
HPLC purified
1
- Application:
- RNA Interference
- Gene:
- V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343745
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to RAF1
- Raf-1 proto-oncogene, serine/threonine kinase (RAF1)
- Raf-1 proto-oncogene, serine/threonine kinase (Raf1)
- Raf-1 proto-oncogene, serine/threonine kinase a (raf1a)
- Raf-1 proto-oncogene, serine/threonine kinase (raf1)
- v-raf-leukemia viral oncogene 1 (Raf1)
- Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S)
- 6430402F14Rik
- AA990557
- BB129353
- c-Raf
- c-raf
- CRAF
- craf
- cRaf
- Craf1
- D830050J10Rik
- NS5
- raf
- Raf-1
- raf1
- RAF1
- v-Raf
Gene-IDs for different species
Protein level used designations for RAF1
- Oncogene RAF1
- RAF proto-oncogene serine/threonine-protein kinase
- proto-oncogene c-RAF
- raf proto-oncogene serine/threonine protein kinase
- C-RAF
- cRaf
- murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV)
- raf-1
- v-raf-1 murine leukemia viral oncogene homolog 1
- murine leukemia viral oncogene homolog
- serine/threonine protein kinase RAF1
- MIL proto-oncogene serine/threonine-protein kinase
- RAF-1
- c-mil protein
- murine leukemia viral (v-raf-1) oncogene homolog 1
- RAF proto-oncogene serine/threonine-protein kinase-like
- Craf1 transforming
- murine sarcoma 3611 oncogene 1
- sarcoma 3611 oncogene
- v-raf-1 leukemia viral oncogene 1
- Proto-oncogene c-RAF
- Raf-1
Proteomics products related to RAF1 Gene
Other products related to RAF1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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