RAN (RAN, Member RAS Oncogene Family, RAN)
Short Description: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease. [provided by RefSeq, Jul 2008].
More information related to gene RAN.
More information related to gene RAN.
Products related to RAN Gene:
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62 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- RAN, Member RAS Oncogene Family (RAN)
- NCBI Accession:
- NM_006325
- Gene ID:
- 5901 (Human, RAN)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4936036
OriGene sr303978
RNAi
RAN
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- RAN, Member RAS Oncogene Family
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343751
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to RAN
- RAN, member RAS oncogene family (RAN)
- RAN, member RAS oncogene family (Ran)
- RAN, member RAS oncogene family S homeolog (ran.S)
- RAN, member RAS oncogene family (ran)
- CG1404 gene product from transcript CG1404-RC (Ran)
- AAF30287
- ARA24
- ara24
- CG1404
- Dmel\CG1404
- dran
- fc16b04
- Gsp1
- gsp1
- l(1)G0075
- ran
- RAN
- Ran
- ran-1
- ran10A
- RANP1
- TC4
- tc4
- wu:fc16b04
Gene-IDs for different species
Protein level used designations for RAN
- GTP-binding nuclear protein Ran
- GTPase Ran
- OK/SW-cl.81
- RanGTPase
- androgen receptor-associated protein 24
- guanosine triphosphatase Ran
- member RAS oncogene family
- ras-like protein TC4
- ras-related nuclear protein
- RAN, member RAS oncogene family
- RAN, member RAS oncogene family pseudogene 1
- CG1404-PA
- CG1404-PB
- Ran GTPase
- ran-PA
- ran-PB
Proteomics products related to RAN Gene
Other products related to RAN such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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